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Methotrexate

Men's Health » Cancer » Methotrexate

Methotrexate is an antimetabolite used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. This medicine works by interfering with cell growth and by suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function. This medicine may also be used to treat other conditions as determined by your doctor including lupus and psoriatic arthritis.

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About Methotrexate:

Product Type: Cancer

Brand name: Methotrexate What is methotrexate? Methotrexate interferes with the growth of certain cells of the body especially cells that reproduce quickly such as cancer cells bone marrow cells and skin cells. Methotrexate is used to treat certain types of cancer of the breast skin head and neck or lung. Methotrexate is also used to treat severe psoriasis and rheumatoid arthritis. Methotrexate is usually given after other medications have been tried without successful treatment of symptoms. Methotrexate may also be used for other purposes not listed in this medication guide. What is the most important information I should know about methotrexate? Methotrexate can cause serious or life-threatening side effects on your liver lungs kidneys and bone marrow (immune system). Do not take this medication in larger amounts or take it for longer than prescribed. Follow the directions on your prescription label. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have liver disease (especially if caused by alcoholism) a blood cell or bone marrow disorder or if you are breast-feeding a baby. This medication can cause birth defects in an unborn baby. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you are pregnant. Use an effective form of birth control whether you are a man or a woman. Tell your doctor if you or your sexual partner become pregnant during treatment. To be sure this medication is not causing harmful effects your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled appointments. There are many other medicines that can interact with methotrexate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. What should I discuss with my healthcare provider before taking methotrexate? Do not use this medication if you are allergic to methotrexate. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have: • liver disease; • alcoholism or cirrhosis of the liver; • a blood cell disorder such as anemia (lack of red blood cells) or leukopenia (lack of white blood cells); • a bone marrow disorder; or • if you are breast-feeding a baby. Methotrexate is sometimes used to treat cancer even when patients do have one of the conditions listed above. Your doctor will decide if this treatment is right for you. Before using methotrexate tell your doctor if you are allergic to any drugs or if you have: • kidney disease; • liver disease; • lung disease or pneumonia; • stomach ulcers; • any type of infection; or • if you are receiving radiation treatments. FDA pregnancy category X. Methotrexate can cause birth defects in an unborn baby. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use birth control to prevent pregnancy while you are using methotrexate whether you are a man or a woman. Methotrexate use by either parent may cause birth defects. Before you start taking methotrexate your doctor may want you to have a pregnancy test to make sure you are not pregnant. If you are a man use a condom to keep from causing a pregnancy while you are using methotrexate. Continue using condoms for at least 90 days after your treatment ends. If you are a woman use an effective form of birth control while you are taking methotrexate and for at least one cycle of ovulation after your treatment ends. Do not give this medicine to a child without the advice of a doctor. Older adults may be more likely to have side effects from this medication. How should I take methotrexate? Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts or take it for longer than recommended by your doctor. Follow the directions on your prescription label. You must use the correct dose of methotrexate for your condition. The medication is sometimes taken only once per week. Some people have died after taking methotrexate every day by accident. Ask your doctor if you have any questions about your dose of methotrexate or how often to take it. This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions. It is important to use methotrexate regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. To be sure this medication is not causing harmful effects your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested and you may need an occasional liver biopsy. Do not miss any scheduled appointments. Store methotrexate at room temperature away from moisture and heat. What happens if I miss a dose? Call your doctor if you miss a dose of methotrexate. What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. An overdose of methotrexate can be fatal. Overdose symptoms may include pale skin easy bruising or bleeding unusual weakness mouth sores nausea vomiting black or bloody stools coughing up blood or vomit that looks like coffee grounds and urinating less than usual or not at all. What should I avoid while taking methotrexate? Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds) especially if you are being treated for psoriasis. Methotrexate can make your skin more sensitive to sunlight and your psoriasis may worsen. Avoid drinking alcohol while taking methotrexate. Methotrexate side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. Stop using methotrexate and call your doctor at once if you have any of these serious side effects: • dry cough shortness of breath; • diarrhea vomiting white patches or sores inside your mouth or on your lips; • blood in your urine or stools; • urinating less than usual or not at all; • fever chills body aches flu symptoms; • sore throat and headache with a severe blistering peeling and red skin rash; • pale skin easy bruising or bleeding weakness; or • nausea stomach pain low fever loss of appetite dark urine clay-colored stools jaundice (yellowing of the skin or eyes). Less serious side effects may include: • nausea vomiting upset stomach; • dizziness tired feeling; • headache; • bleeding of your gums; or • blurred vision. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. What other drugs will affect methotrexate? Before taking methotrexate tell your doctor if you are using any of the following drugs: • azathioprine (Imuran); • chloramphenicol (Chloromycetin); • hydroxychloroquine (Plaquenil Quineprox); • retinol tretinoin (Retin-A) isotretinoin (Accutane); • steroids (prednisone and others); • sulfa drugs such as Azulfidine Bactrim or Septra; • phenytoin (Dilantin); • probenecid (Benemid); • tetracycline (Brodspec Panmycin Sumycin Tetracap); • theophylline (Elixophyllin Slo-Bid Theobid Theo-Dur); • gold treatments such as auranofin (Ridura) or aurothioglucose (Solganol); • oral diabetes medications such as acetohexamide (Dymelor) chlorpropamide (Diabinese) glipizide (Glucotrol) glimepiride (Amaryl) or tolbutamide (Orinase); • penicillin antibiotic such as ampicillin (Principen) amoxicillin (Amoxil Trimox) carbenicillin (Geocillin) cloxacillin (Cloxapen) dicloxacillin (Dynapen) nafcillin (Unipen) oxacillin (Bactocill) penicillamine (Cuprimine Depen) or Bee-Pen Pen-Vee K Veetids; • salicylates such as aspirin Disalcid Doan's Pills Dolobid Salflex Tricosal and others; or • NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin Advil) naproxen (Aleve Naprosyn) diclofenac (Voltaren) diflunisal (Dolobid) etodolac (Lodine) flurbiprofen (Ansaid) indomethacin (Indocin) ketoprofen (Orudis) ketorolac (Toradol) mefenamic acid (Ponstel) meloxicam (Mobic) nabumetone (Relafen) piroxicam (Feldene) and others. This list is not complete and there may be other drugs that can interact with methotrexate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Men's Health: Avodart (Dutasteride) Avodart (Dutasteride) is an androgen hormone inhibitor used in men to treat benign prostatic hyperplasia (BPH) which is swelling of the prostate. This medicine works by lowering the amount of the hormone responsible for prostate growth. Dutasteride reduces urinary blockage and improves urine flow. This medicine should not be used in women and children. Buy Avodart (Dutasteride) and other Men's Health products online at Medstore. About Avodart (Dutasteride): Product Type: Men's Health Brand name: Avodart Generic name: Dutasteride What is the most important information I should know about Avodart? • Before taking Avodart tell your doctor if you have ever had an allergic reaction to this medication or to a similar medicine called finasteride (Propecia Proscar). • Avodart should never be taken by a woman or a child. Avodart can be absorbed through the skin and women or children should not be permitted to handle Avodart capsules. • Although Avodart is not for use by women this medication can cause birth defects if a woman is exposed to it during pregnancy. Avodart capsules should not be handled by a woman who is pregnant or who may become pregnant. • If a woman accidentally comes into contact with this medication from a leaking capsule wash the area with soap and water right away. • Do not donate blood while taking Avodart and for at least 6 months after your treatment ends. Avodart can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains Avodart. What is Avodart? • Avodart prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH). • Avodart is used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate. This medicine helps improve urinary flow and may also reduce your need for prostate surgery later on. • Avodart may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Avodart? • Before taking Avodart tell your doctor if you have ever had an allergic reaction to this medication or to a similar medicine called finasteride (Propecia Proscar). • Avodart should never be taken by a woman or a child. Avodart can be absorbed through the skin and women or children should not be permitted to handle Avodart capsules. • Although Avodart is not for use by women this medication can cause birth defects if a woman is exposed to it during pregnancy. Avodart capsules should not be handled by a woman who is pregnant or who may become pregnant. • If a woman accidentally comes into contact with this medication from a leaking capsule wash the area with soap and water right away. How should I take Avodart? • Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts or take it for longer than recommended by your doctor. • Take each dose with a full glass of water. • Avodart can be taken with or without food. • Swallow the Avodart capsule whole. Do not chew crush or break the capsule. • It is important to take Avodart regularly to get the most benefit. • Do not stop taking Avodart without first talking to your doctor. It may take as long as 3 to 6 months of treatment with Avodart before you notice improvement in your BPH symptoms. • To be sure this medication is helping your condition your prostate will need to be checked on a regular basis. Your PSA (prostate-specific antigen) may also be tested to help detect prostate cancer. It is important that you not miss any scheduled visits to your doctor. • Store Avodart at room temperature away from moisture and heat. Avodart capsules may become soft and leaky or they may stick together if they get too hot. Do not use any capsule that is cracked or leaking. Call your pharmacist for instructions on how to safely dispose of a leaking Avodart capsule. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? • Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Avodart is not expected to produce life-threatening symptoms. What should I avoid while taking Avodart? • Do not donate blood while taking Avodart and for at least 6 months after your treatment ends. Avodart can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains Avodart. What are the possible side effects of Avodart? • Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. • Other less serious side effects are more likely to occur such as: decreased libido (sex drive); decreased amount of semen released during sex; impotence (trouble getting or keeping an erection); or breast tenderness or enlargement. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Avodart? • Before taking Avodart tell your doctor if you are using any of the following drugs: HIV medicines such as indinavir (Crixivan) saquinavir (Invirase) lopinavir/ ritonavir (Kaletra) ritonavir (Norvir) or nelfinavir (Viracept). • If you are using any of these drugs you may not be able to use Avodart or you may need dosage adjustments or special tests during treatment. • There may be other drugs not listed that can affect Avodart. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Generic Avodart (Dutasteride) Dutas Veltride 0.5mg 120 caps 0.5mg 240 caps 0.5mg 60 caps 0.5mg 30 caps 0.5mg 90 caps Dutasteride Avodart